|
KMID : 1007320090150020101
|
|
Journal of the Korean Society of Menopause
2009 Volume.15 No. 2 p.101 ~ p.109
|
|
|
The Predictors of Lumbar Spinal Bone Mineral Density in Pre- and Postmenopausal Women
|
|
Choi Sung-Hyun
Hwang Da-Kyoung
Song Hye-Ryoung
Noh Hae-Jeong
Kang Jin-Yi
Choi Da-Hye
Choi Hee-Jeong
|
|
|
Abstract
|
|
|
Objectives: The objective was to determine predictors of lumbar spinal bone mineral density (BMD) in pre- and postmenopausal women. Also, we investigated factors that affect low BMD (T-score＜?2.0).
Methods: We analyzed the data of 2,474 women over the age of 21 who visited the Health Promotion Center. Personal and medical history was collected. Physical examination and laboratory tests were performed. LS BMD was measured using dual-energy X-ray absorptiometry. We evaluated predictors of LS BMD using multiple regression analysis. Logistic regression analysis was used to determine factors affecting low BMD.
Results: In premenopausal women, LS BMD was correlated with height, weight, body mass index (BMI), body fat%, waist, systolic blood pressure, pulse rate, alkaline phosphatase (ALP), low density lipoprotein cholesterol, fasting glucose, insulin, HOMA-IR, HbA1C, uric acid, and homocysteine levels. In postmenopausal women, LS BMD was correlated with age, height, weight, BMI, body fat%, waist, pulse rate, ALP, uric acid, and homocysteine levels. Among premenopausal women, age, weight, pulse rate, HbA1C, and homocysteine levels were predictors of LS BMD (R2=0.13) and among postmenopausal women, age, weight, and uric acid levels were predictors (R2=0.14). Factors affecting low BMD were age, weight, pulse rate, ALP, and HbA1C in premenopausal women, and age, weight, ALP, and uric acid in postmenopausal women.
Conclusion: In premenopausal women, weight was a major predictor of LS BMD. On the other hand, age was the strongest predictor of LS BMD in postmenopausal women.
|
|
|
KEYWORD
|
|
|
Menopause, Bone mineral density (BMD), Osteoporosis
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|
|